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Open Access Case report

Immune disease expressed in liver and platelets in an adolescent: a case report

Henedina Antunes12, Ruben Rocha1*, Nicole Silva1, Teresa Pontes1, Ana Antunes1 and Sofia Martins1

Author Affiliations

1 Adolescents Unit and Gastrenterology, Hepatology and Nutrition Unit, Pediatrics Department, Braga Hospital, Braga, Portugal

2 Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Campus de Gualtar, 4709-057 Braga, Portugal

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Italian Journal of Pediatrics 2010, 36:42  doi:10.1186/1824-7288-36-42

Published: 11 June 2010

Abstract

We report a case of a 15-year-old boy with autoimmune hepatitis lacking common serologic markers and normal gammaglobulinemia associated with immune thrombocytopenia and family history of psoriasis. He presented to our department with a 4-year history of a cervical posterior lymphadenopathy and recent petechiae. Previous laboratory results 6 months before already showed hepatocellular injury. After exclusion of other causes, the diagnosis of autoimmune hepatitis was made based on clinical grounds, associated immune disorder and histological features of liver biopsy.

The authors alert for this atypical presentation of autoimmune hepatitis and associated immune thrombocytopenia.