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Open Access Highly Accessed Review

Autoinflammatory syndromes: diagnosis and management

Sara De Sanctis*, Manuela Nozzi, Marianna Del Torto, Alessandra Scardapane, Stefania Gaspari, Giuseppina de Michele, Luciana Breda and Francesco Chiarelli

Author Affiliations

Department of Pediatrics, University of Chieti, Via Vestini 5, 66100 Chieti, Italy

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Italian Journal of Pediatrics 2010, 36:57  doi:10.1186/1824-7288-36-57

Published: 3 September 2010

Abstract

During the last decades the description of autoinflammatory syndromes induced great interest among the scientific community. Mainly rheumatologists, immunologists and pediatricians are involved in the discovery of etiopathogenesis of these syndromes and in the recognition of affected patients. In this paper we will discuss the most important clues of monogenic and non-genetic inflammatory syndromes to help pediatricians in the diagnosis and treatment of these diseases.