Erythema multiforme as first sign of incomplete Kawasaki disease
Pediatric Unit, Maternal & Infant Department, “S. Chiara” University-Hospital, Via Roma 67, Pisa 56126, Italy
Italian Journal of Pediatrics 2013, 39:11 doi:10.1186/1824-7288-39-11Published: 13 February 2013
Incomplete Kawasaki disease represents a diagnostic challenge for pediatricians. In the absence of classical presentation, the laboratoristic evaluation of systemic inflammation can help in placing the correct diagnosis to promptly start adequate therapy. Erythema multiforme is an acute, self-limiting condition considered to be a hypersensitivity reaction commonly associated with various infections or medications. This aspecific skin condition has been rarely described as a sign of Kawasaki disease. We report on the case of a 4 years old boy presenting high-grade fever associated with erythema multiforme and evidence of systemic inflammation who showed a good response to prompt treatment with intravenous immunoglobulins.